Seminal vesicle intrafraction motion 83 Supplementary E Figure S4 provides an overview of the included number of samples over time. As not all radiotherapy fractions take the same amount of time of dose delivery, the length of the beam-on time and thus the length of cine-MR acquisition varies. This graph shows that 247 cine-MR dynamics were available and included at time point 0 min, and only 50% of this number (~125 cine-MR dynamics) remained available at the time point of 10 min. With a reducing number of samples, the uncertainty of motion statistics grows. Figure S4 – Graph showing the number of included cine-MR dynamics (thus: samples) for each point in time. 4
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