Joëlle Schutten

Comparison of two methods for the assessment of intra-erythrocyte magnesium and its determinants 61 3 dIEM, mmol/1012 cells iIEM, mmol/1012 cells Plasma magnesium, mmol/L Determinants Univariable St. β (95% CI) Multivariable St. β (95% CI) Univariable St. β (95% CI) Multivariable St. β (95% CI) Univariable St. β (95% CI) Multivariable St. β (95% CI) Hematology Hemoglobin, mmol/L 0.08 (0.03; 0.13)* 0.11 (0.05; 0.17)* 0.08 (0.03; 0.12)* 0.11 (0.05; 0.18)** 0.11 (0.06; 0.16)** 0.15 (0.09; 0.21)** Hematocrit, v/v 0.06 (0.01; 0.10)* 0.05 (-0.01; 0.11) 0.04 (-0.01; 0.08) 0.03 (-0.03; 0.09) 0.13 (0.08; 0.18)** 0.17 (0.11; 0.23)** MCV, fL 0.27 (0.22; 0.32)** 0.24 (0.20; 0.29)** 0.26 (0.22; 0.31)** 0.24 (0.19; 0.28)** 0.01 (-0.04; 0.06) -0.02 (-0.07; 0.04) Multivariable models were adjusted for age, sex, BMI, eGFR (< 90 ml/min/1.73m2), plasma sodium and plasma potassium, and smoking and alcohol consumption. Abbreviations: dIEM, direct intra-erythrocyte magnesium; iIEM, indirect intra-erythrocyte magnesium; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c, MCV, mean corpuscular volume,*p <0.05, **p <0.001 Table 2. (Continued)

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