Joëlle Schutten

Chapter 3 62 Table 3. Subgroup analyses1 with dIEM, iEM and plasma magnesium as dependent variable (stratified for age and sex). dIEM,mmol/1012 cells iIEM,mmol/1012 cells Plasma magnesium,mmol/L Determinants Subgroup Univariable St. β (95% CI) Multivariable St. β (95% CI) Univariable St. β (95% CI) Multivariable St. β (95% CI) Univariable St. β (95% CI) Multivariable St. β (95% CI) Age, years Males 0.06 (-0.02; 0.13) 0.05 (-0.04; 0.14) 0.06 (-0.01; 0.14) 0.07 (-0.02; 0.16) -0.05 (-0.12; 0.03) -0.05 (-0.14; -0.05)* Females 0.22 (0.16; 0.29)** 0.16 (0.08; 0.24)** 0.19 (0.13; 0.26)** 0.14 (0.07; 0.22)* 0.18 (0.12; 0.25)** 0.11 (0.03; 0.19)* Sex, female Age < 55 -0.05 (-0.11; 0.01) 0.01 (-0.05; 0.08) .. .. .. .. Age ≥ 55 0.08 (0.002; 0.16)* 0.10 (0.01; 0.18)* .. .. .. .. Body mass index, kg/m2 Males -0.01 (-0.09; 0.08) -0.01 (-0.10, 0.07) .. .. .. .. Females 0.08 (0.02; 0.14)* 0.06 (-0.003; 0.11) .. .. .. .. Age < 55 .. .. .. .. -0.03 (-0.08; 0.03) -0.05 (-0.11; 0.01) Age ≥ 55 .. .. .. .. -0.11 (-0.20; -0.02)* -0.11 (-0.20; -0.02)* Waist circumference, cm Males 0.01 (-0.07; 0.10) 0.02 (-0.15; 0.18) .. .. .. .. Females 0.11 (0.04; 0.17)* -0.004 (-0.12; 0.12) .. .. .. .. Age < 55 .. .. .. .. 0.04 (-0.02; 0.10) -0.02 (-0.09; 0.04) Age ≥ 55 .. .. .. .. -0.11 (-0.20; -0.02)* -0.08 (-0.18; 0.01) Log10 glucose, mmol/L Age < 55 .. .. .. .. -0.14 (-0.20; -0.07)** -0.17 (-0.24; -0.10)** Age ≥ 55 .. .. .. .. -0.23 (-0.31; -0.15)** -0.17 (-0.26; -0.07)* Log10 HbA1c, mmol/mol Age < 55 .. .. .. .. -0.06 (-0.12; -0.001)* -0.09 (-0.15; -0.03)** Age ≥ 55 .. .. .. .. -0.25 (-0.34; -0.17)** -0.20 (-0.30; -0.11)** Males .. .. .. .. -0.21 (-0.29; -0.14)** -0.22 (-0.31; -0.14)** Females .. .. .. .. -0.003 (-0.07; 0.06) -0.09 (-0.16; -0.01)* Log10 triglyerides, mmol/L Age < 55 0.10 (0.04; 0.15)* 0.08 (0.02; 0.14)* .. .. 0.08 (0.02; 0.13)* 0.07 (0.01; 0.13)* Age ≥ 55 0.10 (0.004; 0.19)* 0.11 (0.02; 0.21)* .. .. -0.04 (-0.14; 0.07) 0.01 (-0.09; 0.12) Renal function

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