Elke Wynberg

Chapter 8 258 Supplementary Table S1. Socio-demographic and clinical characteristics of matched vaccinated and unvaccinated participants, among participants with PASC at 3 months after illness onset Total Exposure group p-value Unvaccinated Vaccinated N=68 N=32 N=36 0.89 Sex 0.72 Male 24 (35%) 12 (38%) 12 (33%) Female 44 (65%) 20 (63%) 24 (67%) Age, years 52.5 (36.5-62.0) 48.5 (37.0-63.0) 53.5 (34.5-61.0) 0.74 BMI, kg/m2 25.9 (22.6-29.4) 26.7 (23.0-29.4) 25.2 (22.6-29.4) 0.62 BMI category 0.49 Normal weight 30 (44%) 12 (38%) 18 (50%) Overweight 23 (34%) 13 (41%) 10 (28%) Obese 15 (22%) 7 (22%) 8 (22%) Highest level of education 0.89 None, primary or secondary education 14 (21%) 7 (22%) 7 (19%) Vocational training 20 (29%) 10 (31%) 10 (28%) University education 34 (50%) 15 (47%) 19 (53%) Number of COVID-19 high-risk comorbidities 0.76 0 38 (56%) 19 (59%) 19 (53%) 1 16 (24%) 7 (22%) 9 (25%) 2 11 (16%) 4 (13%) 7 (19%) 3 or more 3 (4%) 2 (6%) 1 (3%) Clinical severity score 0.0040 Mild 14 (21%) 3 (9%) 11 (31%) Moderate 41 (60%) 18 (56%) 23 (64%) Severe/critical 13 (19%) 11 (34%) 2 (6%) Presence of symptom at matched time-point†: 48 (73%) 23 (74%) 25 (71%) 0.80 Fatigue 29 (53%) 15 (54%) 14 (52%) 0.90 Dyspnoea 19 (40%) 7 (35%) 12 (44%) 0.51 Headache 19 (32%) 10 (37%) 9 (27%) 0.42

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