Martine De Herdt

124 Chapter 4 Supplementary table 4: Possible MET protein products, which are identical for both the N- and C-terminus. N-terminal MET protein products C-terminal MET protein products Mw (kDa) Non-reducing Mw (kDa) reducing conditions Membrane spanning Protein product Ref. Mw (kDa) reducing conditions Membrane spanning Protein product Ref. p170 p170 No Single chain MET precursor (4) p170 No Single chain MET precursor (4) p190 p145β Yes Mature, cell surface associated disulphide linked heterodimer (190 kDa) having an extracellular α-chain (50 kDa) and a transmembranous β-chain (145 kDa) (4, 5) p145β Yes MET full-length β-subunit (4)

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