Part I | Chapter 4 78 vesicle intrafraction motion is larger than prostate intrafraction motion in the cranial direction, but not in the left-right and anterior-posterior direction. In addition, significant larger spread in rotations about the left-right, anterior-posterior and caudal-cranial axes was found for the seminal vesicles relative to the prostate. The results have shown that in the case of intrafraction motion correction for MRI-guided radiotherapy not only translation, but especially seminal vesicle rotation should be corrected for when including seminal vesicles as target. With the gained insight on seminal vesicle intrafraction motion, we will proceed towards MRI-guided hypofractionated radiotherapy for intermediate and high-risk prostate cancer patients.
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