Part II | Chapter 8 168 Figure 3 – Nomogram based on model 2 for prediction of biochemical failure among patients who underwent FS-HDR-BT. Legend: PSA = Prostate-specific antigen. PSADT = PSA-doubling time. %PSA = Percentage PSA. nPSA = PSA nadir. BF = Biochemical failure. Probabilities of biochemical failure within 12, 24, and 36 months can be calculated. The model can be used online through: https://fs-hdr-bt-prediction.shinyapps.io/model2/. As an example, for the same patient (72 years old, PSA level 6.0 ng/mL, and a pre-salvage PSADT of 25 months) with no seminal vesicle involvement, PSA nadir after 6 months and a PSA reduction of 90%, the score based on model 2 would be 313, with estimated bDFS probabilities of 98% (95% CI: 96-100%), 80% (95% CI: 71-91%) and 52% (95% CI: 36-74%) at 12, 24, and 36 months.
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