Hylke Salverda

134 Chapter 7 Supplemental material Supplementary table 1: Pre-implementation Automated Oxygen Control loss to follow-up characteristics Patient characteristics Pre-AOC Data available n = 269 Loss to follow-up n = 20 p value* Gestational age in weeksdays, median [IQR] 282 [265 – 290] 283 [276 – 291] 0.09 Birth weight in grams, mean (SD) 1033 (284) 1080 (378) 0.49 Males, n (%) 151 (56.1) 11 (55.0) 0.92 Antenatal corticosteroids, n (%) 227 (85.3) 19 (95.0) 0.23 Caesarean delivery, n (%) 128 (47.6) 15 (75.0) 0.02 Multiple pregnancy, n (%) 104 (38.7) 11 (55.0) 0.15 of which monochorionic twins, n (%) 64 (61.5) 7 (63.6) 0.29 Perinatal asphyxia, n (%) 4 (1.5) 0 (0.0) 1.00 Apgar score at 5 minutes, median (range) 8 (2-10) 8.5 (6-10) 0.03 Intraventricular haemorrhage (≥ stage 2), n (%) 54 (20.1) 1 (5.0) 0.14 Periventricular leukomalacia (≥ stage 2), n (%) 3(1.1) 1 (5.0) 0.25 Received laser coagulation for ROP, n (%) 12 (5.2) 1 (5.9) 1.00 Bronchopulmonary dysplasia severe, n (%) 34 (14.4) 2 (11.1) 0.29 moderate, n (%) 12 (5.1) 0 (0.0) mild, n (%) 43 (18.2) 1 (5.6) AOC, Automated Oxygen Control; ROP, Retinopathy of prematurity; *Statistical analysis with independent T-test, chi-square, Fisher’s exact, or nonparametric Mann-Whitney U test as appropriate

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