128 Chapter 7 Table 2 continued. Outcomes at two years follow-up Pre-AOC Post-AOC p value* Cerebral palsy GMFCS, n (%) None 200 (84.7) 190 (88.0) 0.73 Level 1 30 (12.7) 21 (9.7) Level 2 4 (1.7) 4 (1.9) Level 3 2 (0.8) 1 (0.5) Level 4 0 (0) 0 (0) Level 5 0 (0) 0 (0) Readmissions until follow-up, n (%) none 130 (57.0) 149 (69.3) 0.01 1-3 83 (36.4) 50 (23.3) >3 15 (6.6) 17 (7.4) AOC, Automated Oxygen Control; NDI, neurodevelopmental impairment; BSID, Bayley Scales of Infant and Toddler Development; CBCL, Child Behaviour Checklist; GMFCS, Gross Motor Function Classification System. *Statistical analysis with independent T-test, chi-square, Fishers’ exact, or nonparametric Mann-Whitney U test as appropriate The median Bayley-III composite motor score was 97 [89 – 107] pre-AOC and 98 [89 – 109] post-AOC (p=0.18). The composite cognitive score was 96 [87 – 101] vs. 96 [91 – 105] (p=0.23). No significant differences were found in rates of scores between 1-2 SD under the mean (score 70-85) and below -2 SD under the mean (score <70), for motor nor cognitive. Motor scores respectively for pre- vs. post-implementation cohorts: 12.6% (25/199) of the children had scores between 1-2 SD under the mean and 2.5% (5/199) below -2 SD vs. 12.8% (25/195, p=0.94) and 5.6% (11/195, p=0.12) after implementation. Cognitive scores in the pre-implementation group were found in 13.9% (31/232) between 1-2 SD under the mean and under 2 SD under the mean in 3.0% (7/232) vs. 12.7% (26/204, p=0.85) and 3.4% (7/204, p=0.81) respectively. We found no significant differences between groups in externalising (51±10 vs. 50±10 , p=0.69) or internalising (47 [41 – 55] vs. 47 [41 – 55], p=0.59) problem behaviour scores. Neurological examination, cerebral palsy GMFCS scores, visual impairment and hearing loss yielded no significant differences. However, parents did report significantly fewer readmissions until the moment of follow-up in the post-AOC group (p=0.002).

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