Femke Mathot

Chapter 1 General introduction and outline of this thesis 11
Chapter 2 Targeted stimulation of mesenchymal stem cells in peripheral nerve repair 27
Chapter 3 Adhesion, distribution and migration of differentiated and undifferentiated mesenchymal stem cells (MSCs) seeded on nerve allografts 43
Chapter 4 Gene expression profiles of differentiated and undifferentiated adipose derived mesenchymal stem cells dynamically seeded onto a processed nerve allograft 59
Chapter 5 New methods for objective angiogenesis evaluation of rat nerves using microcomputed tomography scanning and conventional photography 79
Chapter 6 Adipose derived Mesenchymal Stem Cells seeded onto a decellularized nerve allograft enhances angiogenesis in a rat sciatic nerve defect model 93
Chapter 7 Functional outcomes of nerve allografts seeded with undifferentiated and differentiated mesenchymal stem cells in a rat sciatic nerve defect model 109
Chapter 8 Introducing human adipose derived mesenchymal stem cells to Avance® nerve grafts and NeuraGen® nerve guides 127
Chapter 9 Gene expression profiles of human adipose-derived mesenchymal stem cells dynamically seeded on clinically available processed nerve allografts and collagen nerve guides 143
Chapter 10 General discussion and future perspectives 167
Chapter 11 Summary & Dutch summary 185
Research data management 197
List of publications 199
PhD Portfolio 201
Curriculum Vitae 203
Dankwoord 205

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