Anna Brouwer

130 Chapter 6 Abstract Purpose To describe the retinal function as measured by full-field electroretinogram (ERG) in patients with juvenile idiopathic arthritis (JIA) associated uveitis. Methods ERGs were measured according to an extended ISCEV protocol. Results Ten of the 16 uveitis eyes (8 patients) showed ERG abnormalities. The type of ERG abnormalities varied amongst patients and occurred in both amplitudes and implicit times, in a-waves, b-waves, 30 Hz flicker response and in both the dark adapted and the light adapted ERG. Five eyes had an active inflammation at the time of the ERG recording; all of these showed ERG abnormalities. Five out of eleven inactive uveitis eyes showed ERG abnormalities. No correlations were found between ERG abnormalities and the duration of uveitis, mean deviation on visual field analysis, or central macular thickness. None of the eyes had severe media opacities which could have explained the observed ERG abnormalities. Conclusion Even though JIA is a typical anterior uveitis, the retinal function can be affected in this type of uveitis.