Maarten van Egmond

51 The pre- and postoperative course of functional status 3 P- value T3 Δ T3-T1 (95% CI) P- value T4 Δ T4-T1 (95% CI) P- value .19 108.2 (23.3) -2.8 (-6.8 to 1.3) .18 104.8 (30.1) -6.2 (-11.3 to -1.1) .02 .09 88.4 (33.6) -37.2 (-43.0 to -31.4) <.001 120.4 (38.1) -4.4 (-10.5 to 1.8) .16 .91 87.6 (34.0) -32.2 (-37.7 to -26.7) -.70 119.1 (38.1) -2.3 (-8.8 to 4.2) .48 .001 147.5 (37.2) -48.4 (-54.0 to -42.7) <.001 191.2 (34.4) -5.7 (-12.6 to 1.2) .10 .002 - - - 49.2 (17.1) 4.7 (0.7 to 8.7) .02 <.001 - - - 71.8 (18.1) -2.5 (-6.7 to 1.8) .25 <.001 - - - 453.0 (539.4) 136.8 (-106.8 to 380.5) .27 European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30: scores range from 0 to 100 with high scores indicating a better quality of life. LAPAQ, LASA physical activity questionnaire: total amount of activities in kilocalories per day. P -value ≤ .05 is considered significant. Figure 2. Postoperative complications according to the Clavien Dindo classification (N = 155) Grade I: Any deviation from the normal postoperative course without pharmacologic treatment or surgical, endoscopic, and radiological interventions; Grade II: Requiring pharmacologic treatment with drugs other than ones allowed for grade I complications; Grade III: Requiring surgical, endoscopic, or radiologic intervention not under general anesthesia (IIIa), under general anesthesia (IIIb); Grade IV: Life-threatening complications requiring IC/ICU management, single-organ dysfunction (including dialysis) (IVa), multiorgan dysfunction (IVb); Grade V: Death of a patient.