Table of Content List of Abbreviations 4 Introduction CHAPTER 1 9 General Introduction, Objectives and Thesis Outline Results CHAPTER 2 33 Phototoxicity and Cell Passage A ect Intracellular Reactive Oxygen Species Levels and Sensitivity Towards Non-Thermal Plasma Treatment in Fluorescently-Labeled Cancer Cells CHAPTER 3 63 Enhancing Anti-Tumor Immunity in Head and Neck Cancer: NonThermal Plasma as a Promising Adjuvant to Cisplatin-Based Therapy CHAPTER 4 113 E ect of Plasma-Induced Oxidation on NK Cell Immune Checkpoint Ligands: A Computational-Experimental Approach Discussion and Future Perspectives CHAPTER 5 157 The pro- and anti-tumoral properties of gap junctions in cancer and their role in therapeutic strategies CHAPTER 6 201 General Discussion and Project Positioning Summary 219 Samenvatting 224 Curriculum Vitae 228 Dankwoord 237
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