28 Chapter 2 Author, Year Country Design Setting, Single/Multi centre Guideline topic Van der Putten, 2013 [48] Netherlands Cluster Randomized Controlled Trial Nursing homes - Within 100km radius of the centre of the Netherlands, Multi centre Oral care Lozano, 2004 [49] USA Cluster Randomized Controlled Trial Primary care paediatric practices, Multi centre Other - Asthma treatment Clark, 2001 [50] United Kingdom Before-After Hospital - a large teaching hospital, Single centre Other - Blood transfusion Tian, 2017 [51] Belgium Before-After Hospital, Single centre Other - Cancer related fatigue Van Lieshout, 2016 [52] Netherlands Cluster Randomized Controlled Trial General Practices, Multi centre Other - Cardiovascular risk management in general practices Downey, 2015 [53] Australia Before-After Hospital - A 18 bed Head, neck and lung medical oncology ward, Single centre Other - Crushing medication in case of Tube feeding only Sipila, 2008 [54] Finland Before-After General practices - 31 in total, Multi centre Other - Early detection, prevention and treatment of CVD (Cardiovascular disease) Snelgrove-Clarke, 2015 [55] Canada RCT Hospital - University affiliated teaching hospital in Atlantic, Single centre Other - Foetal Health Surveillance Featherston, 2018 [56] USA Before-After Community mental health centre, Single centre Other - Paediatric mental healthcare Jagt-van Kampen, 2015 [57] Netherlands Before-After Hospital - Academic children’s hospital, Single centre Other - Paediatric palliative care Duff, 2013 [58] Australia Before-After Hospital - a 250-bed magnet designated private hospital, Single centre Other - Prevention of venous thromboembolism Vander Weg, 2017 [59] USA Before-After Hospital - General medical units of four US Department of Veterans Affairs hospitals, Multi centre Other - Smoking cessation Reynolds, 2016 [60] USA Before-After Hospital - Neuro critical care unit, Single centre Other - Stroke care Cheater, 2006 [61] United Kingdom Cluster Randomized Controlled Trial Family practice, Multi centre Other - Urinary incontinence Savvas, 2014 [62] Australia Before-After Nursing home - Residential aged care facilities across three Australian states, Multi centre Pain - Australian Pain Society
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