Caitlin Vink

Introduction 9
Chapter 1. General introduction 9
Part 1. Endotypes of Chronic Coronary Syndrome 19
Chapter 2 Sex differences in prevalence and outcomes of the different endotypes of chronic coronary syndrome in symptomatic patients undergoing invasive coronary angiography: Insights from the global ILIAS invasive coronary physiology registry 21
Chapter 3 Impact of sex on the assessment of the microvascular resistance reserve 43
Chapter 4 Meta-analysis and systematic review of coronary vasospasm in ANOCA patients 57
Part 2. Myocardial blood volume as driver of ANOCA 85
Chapter 5 Reduced Microvascular Blood Volume as a Driver of Coronary Microvascular Disease in Patients With Non obstructive Coronary Artery Disease: Rationale and Design of the MICORDIS Study 87
Chapter 6 The role of myocardial blood volume in the pathophysiology of angina with non-obstructed coronary arteries: The MICORDIS study 109
Part 3. Quantitative perfusion CMR in ANOCA 141
Chapter 7 Clinical implementation of a fully automated quantitative perfusion cardiovascular magnetic resonance imaging workflow with a simplified dual-bolus contrast administration scheme 143
Chapter 8 Quantitative Perfusion by Cardiac Magnetic Resonance Imaging For Diagnosing Patients with Angina with Non Obstructive Coronary Artery Disease 165
Part 4. Summary of the thesis, discussion and future perspectives 191
Chapter 9. English Summary 193
Chapter 10. General discussion and future perspectives 199
Chapter 11. Nederlandse samenvatting 211
Appendices 217
List of abbreviations 218
List of publications 220
PhD portfolio 222
Dankwoord 224
About the author 229

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