77 Meta-analysis and systematic review of coronary vasospasm in ANOCA patients spasm was found in Western World population compared to Asian population. Disabling symptoms during life are the most important issue for ANOCA patients while further having a rather good prognosis. As the prevalence of CAS is high in ANOCA patients additional coronary spasm provocation testing should follow when obstructive coronary artery disease is ruled out in both men and women. In this, distinguishing between epicardial and microvascular spasm will lead to correct diagnosis and tailored treatment. Furthermore, this study emphasizes the need for unambiguous diagnostic criteria and protocols in ANOCA patients and the implementation of those. 4
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