49 Impact of sex on the assessment of the microvascular resistance reserve Table 2. Angiographic and physiological characteristics Interrogated vessel Total Female Male P-value LAD, % 59 (57 – 62) 64 (61 – 68) 57 (56 – 60) <0.005 LCX, % 18 (16 – 20) 16 (13 – 19) 19 (17 – 21) 0.079 RCA, % 22 (20 – 24) 20 (17 – 23) 23 (22 – 25) 0.039 QCA Analysis Diameter stenosis, % 51 ( 50 – 53) 49 (48 – 51) 52 (51 – 53) 0.009 Minimal Lumen Diameter, 1.59 (1.54 – 1.64) 1.62 (1.55 – 1.70) 1.57 ( 1.53 – 1.61) 0.293 Lesion Length, mm 15.1 (14.1 – 16.1) 14.1 (12.7 – 15.5) 15.5 (14.7 – 16.3) 0.098 Physiological Assessment Baseline Aortic Pressure 98 ( 96 – 99) 101 (99 – 102) 96 (95 – 97) <0.005 Distal Pressure 90 (89 – 91) 93 (92 – 95) 89 (88 – 90) <0.005 Tmn 0.74 (0.71 – 0.78) 0.64 (0.59 – 0.69) 0.78 (0.75 – 0.82) <0.005 APV 17 (16 – 18) 17 (17 – 18) 17 (16 – 18) 0.780 Hyperemic Aortic Pressure 90 (89 – 91) 93 (91 – 95) 89 (88 – 90) <0.005 Distal Pressure 74 (73 – 76) 78 (76 – 79) 73 (72 – 74) <0.005 Tmn 0.29 (0.27 – 0.31) 0.27 (0.25 – 0.29) 0.30 (0.29 – 0.32) 0.005 APV 38 (36 – 39) 37 (35 – 39) 38 (37 – 39) 0.488 Physiological indices Resting Pd/Pa 0.92 (0.91 – 0.93) 0.92 (0.91 – 0.93) 0.92 (0.92 – 0.93) 0.819 FFR 0.82 (0.81 – 0.83) 0.83 (0.82 – 0.84) 0.81 (0.81 – 0.82) 0.030 HMR 2.3 (2.2 – 2.4) 2.4 (2.2 – 2.5) 2.2 (2.1 – 2.3) 0.135 IMR 21 (19 – 22) 20 (19 – 22) 21 (20 – 22) 0.811 CFR 2.6 (2.5 – 2.7) 2.5 (2.4 – 2.6) 2.7 (2.6 – 2.7) <0.005 MRR 3.4 (3.3 – 3.5) 3.2 (3.1 – 3.3) 3.5 (3.3 – 3.5) <0.005 3
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