Caitlin Vink

174 Chapter 8 Rest Stress Rest Stress Rest MBF StressMBF MPR Figure 2. Abnormal Quantitative Perfusion in ANOCA Patient. Example of acquired images in an ANOCA patient Abbreviations: MBF: Myocardial Blood Flow; MPR: Myocardial Perfusion Reserve Figure 3. Quantitative perfusion CMR, in ANOCA patients compared to healthy controls. (A) Rest perfusion showed similar myocardial blood flow, while (B) stress myocardial blood flow was significantly lower in ANOCA patients, also, (C) MPR was significantly lower in ANOCA patients compared to healthy controls. Data are presented as mean ± SD Abbreviations: MBF: Myocardial Blood Flow; MPR: Myocardial Perfusion Reserve Myocardial perfusion across various coronary territories was assessed. Resting MBF showed no significant differences between groups in any coronary territory, while stress MBF was significantly lower in ANOCA patients in all coronary territories (Table 2). MPR was significantly reduced in the RCA territory among ANOCA patients compared to healthy controls (2.16 ± 0.71 vs 2.69 ± 0.69, respectively p = 0.010), but no significant differences were found in both the LAD and RCX territories. Supplementary Table 3 provides an overview of MPR per participant across different coronary territories, highlighting variations within participant. The RCA had the highest prevalence of exhibiting the lowest MPR of all coronary territories within participants, observed in 21 (42.9%) participants. In

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