101 Rational and Design of the MICORDIS study at rest, during administration of an intravenous bolus of contrast gadolinium (Dotarem 0.075 mmol/kg). Stress perfusion CMR-derived MPRI will be calculated (Figure 5). Figure 4. The CMR-protocol consist of stress- and rest imaging, including long axis cine imaging to quantify left ventricular function, myocardial T1-mapping to quantify extracellular volume fraction, perfusion scans including adenosine stress and rest perfusion scan to quantify perfusion using myocardial perfusion reserve index (MPRi), and late gadolinium enhancement (LGE) imaging which is performed to characterize myocardial tissue together with native T1-mapping. Hyperenhancement with LGE is used to quantitatively assess myocardial infarct scar burden. Abbrevations: CMR: Cardiac Magnetic Resonance; LAX: Long axis; SAX: Short axis; IV: intravenous; AIF: Arterial input function 5
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