Chapter 4 130 Figure 10: Comparison of significant differentially expressed genes of neuron lineage clusters at both day 100 and day 150. Log 2-fold changes at day 100 and day 150 of significant genes in the inhibitory neural progenitor 1 (NP1), somatostatin (SST) and GABAergic neuron clusters for the contrasts A-B) HD x GLD, D-F) HD x 4H, G-I) HD x CD. Blue: genes upregulated compared to HD. Red: genes downregulated compared to HD. Gray: genes that do not exceed the significance threshold. A, D, E) The inhibitory NP1 cluster is depicted using a volcano plot of day 150 since there were no significant genes at day 150.
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