Chapter 4 120 ▲ Figure 4: Comparison of the isogenic pairs HD2.2 x KI and HD2.2 x KO at d150. Comparison displays the log fold changes of A-E) genes significant in both contrasts, F-J) one of the contrasts and K-O) all genes. Comparison is done at day 150 for the five cell clusters OPC, proliferation OPC, oligodendrocytes, astrocytes and NPC. Blue: genes upregulated in both contrasts. Red: genes downregulated in both contrasts. Black: genes are inconsistently up & down regulated between the contrasts. Pearson correlation coefficient is displayed in the graph.
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