94 Chapter 2 Appendix D – Overview of literature regarding the historical trends and drivers (Continued) Number Authors Year Title Trend in blood demand Driver: Cost 94 World Health Organization 2013 WHO Expert Committee on Biological Standardization, 62nd report^ No specific trend, but provides committee conclusions on blood product standardization 95 World Health Organization 2016 A guide to establishing a national haemovigilance system^ No specific trend, but provides guidelines for hemovigilance implementation 96 World Health Organization 2016 Establishing External Quality Assessment Programmes for Screening of Donated Blood for TransfusionTransmissible Infections - Implementation Guide^ No specific trend, but provides implementation guidelines for EQA programs 97 World Health Organization 2017 Global Status Report on Blood Safety and Availability, 2016^ No specific trend, yet provides global overview of blood safety and availability 98 Wortham, S. T. O., G. A.; Wenz, B. 2003 A brief history of blood filtration: clot screens, microaggregate removal, and leukocyte reduction No specific trends, yet focus on safety and organizational issues 99 Yerrabothala, S. D., K. P.; Szczepiorkowski, Z. M.; Dunbar, N. M. 2014 Significant reduction in red blood cell transfusions in a general hospital after successful implementation of a restrictive transfusion policy supported by prospective computerized order auditing Decreased
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