88 Chapter 2 Appendix D – Overview of literature regarding the historical trends and drivers (Continued) Number Authors Year Title Trend in blood demand Driver: Cost 74 Tinegate, H. P., K.; Murphy, M.; Babra, P.; Grant-Casey, J.; Hopkinson, C.; Hyare, J.; Rowley, M.; Seeney, F.; Watson, D.; Wallis, J. 2016 Where do all the red blood cells (RBCs) go? Results of a survey of RBC use in England and North Wales in 2014 Decreased 75 Vamvakas, E. C. B., M. A. 2010 Blood still kills: six strategies to further reduce allogeneic blood transfusionrelated mortality No trend mentioned explicitly, but focus on safety 76 van der Poel, C. L. J., M.P.; Behr-Grossmm M.-E. 2011 Trends and Observations on the Collection, Testing and Use of Blood and Blood Components in Europe; 2001-2005 Report Increased 77 van Hoeven, L. K., Rianne; Koffijberg, Hendrik; Roes, Kit; Janssen, Mart 2016 Historical time trends in red blood cell usage in the Netherlands Decreased (for surgical use); increased (for medical use) 78 Vincent, J. L. H., L. A. 2013 What’s new in transfusion policies? Decreased ( the premise of the paper) 79 Vincent, J. L. S., Y.; Lelubre, C. 2014 The future of observational research and randomized controlled trials in red blood cell transfusion medicine No specific trend in blood demand but a comparative review of observational and RCTs in ICU setting 80 Volken, T. B., A.; Castelli, D.; Fontana, S.; Frey, B. M.; Rusges-Wolter, I.; Sarraj, A.; Sigle, J.; Thierbach, J.; Weingand, T.; Taleghani, B. M. 2018 Red blood cell use in Switzerland: trends and demographic challenges Increased (forecasting) 81 Wahl, S. Q., K. C. 2009 Current issues in blood transfusion for sickle cell disease Increased
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