Praiseldy Langi Sasongko

168 Chapter 4 Table S1: Overview of the opportunities, threats, and mitigating measures per theme (indepth version of Table 3 in the main manuscript) (Continued) 10 Disruptive events - This includes threats regarding societal, economical, ecological, political, or operational events. Opportunities/threats • Acute situation: national disaster increases demand • Non-acute situation: overpopulation and aging elderly population increases demand • Dutch government stops regulating Sanquin’s annual budget Threats • Societal: In an acute situation, too many donors donating leading to a wastage of blood; in non-acute situation, there is insufficient blood donors; natural disasters occur or an infectious disease breakout prevents donors from donating • Economical: Sanquin’s privatized entities become bankrupt • Ecological: emerging viruses; major pandemic; emerging pathogens due to traveling; transfusiontransmissible viruses or infections; emerging side effects of transfusions • Political: instability, war, blood scandal, terrorist attack, cyber threat • Operational: Massive long-term power failure from major environmental incident affecting infrastructure, delivery of services, spoilage of inventory Mitigating measures • Sanquin creates/consolidates emergency plans that can be easily activated during a disruptive event, that includes: 1. internal communication plan (for all employees) 2. external communication plan (for donors and hospitals) 3. Sanquin operational plan (e.g. testing) with national operational plan (with Ministry of Health and RIVM) 4. international operational plan (e.g. importing products from a neighboring country) • During acute situations, careful communication and monitoring with willing donors (i.e. via social media)- -when supply exceeds demand, provide donation alternatives • For economical, Sanquin creates transparency and disentangling economic interconnections amongst its entities

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