Maaike Swets

Chapter 1 Introduction and outline of the thesis 9
Part I Infectious disease surveillance 21
Chapter 2 Use of proxy indicators for automated surveillance of severe acute respiratory infection, the Netherlands, 2017- 2023: a proof-of-concept study 23
Chapter 3 Using laboratory test results for surveillance during a new outbreak of acute hepatitis in 3 week to 5 year old children in the United Kingdom, the Netherlands, Ireland and Curaçao: observational cohort study 45
Part II Causal inference and real-world data 75
Chapter 4 SARS-CoV-2 co-infection with influenza viruses, respiratory syncytial virus, or adenoviruses 77
Chapter 5 A comparison of the effectiveness of different doses of tocilizumab and sarilumab in the treatment of severe COVID-19: a natural experiment due to drug shortages 95
Chapter 6 Influenza season and outcome after elective cardiac surgery: an observational cohort study 119
Part III Facilitating causal inference 137
Chapter 7 Evaluation of pragmatic oxygenation measurement as a proxy for Covid-19 severity 141
Chapter 8 Clinical sub-phenotypes of Staphylococcus aureus bacteraemia 175
Chapter 9 Summary and general discussion 199
Nederlandse samenvatting 224
Acknowledgements 241
List of publications 243
Curriculum Vitae 247

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