170 Chapter 7 Measure Distribution/ Event rate Estimated treatment effect Total n (β = 80% 2p = 0.05) S/F94 day 5 Mean = 2.39 SD = 1.29 ρ vs Day 0 = 0.31 Δ S/F94: 0.180 1,444 S/F94 day 8 Mean = 2.73 SD = 1.51 ρ vs Day 0 = 0.28 Δ S/F94: 0.158 2.684 WHO day 5 4: 2,275/9,998 5: 2,433/9,998 6: 2,736/9,998 7: 363/9,998 8: 1,145/9,998 9: 418/9,998 10: 628/9,998 Proportional odds ratio: 0.84 3,331 WHO day 8 4: 2,801/8,207 5: 1,525/8,207 6: 1,445/8,207 7: 429/8,207 8: 968/8,207 9: 343/8,207 10: 696/8,207 Proportional odds ratio: 0.84 3,222 1-level sustained improvement 13,437/30,060 (44.7%) Risk ratio: 1.03 6,756 2-level sustained improvement 5,411/30,060 (18.0%) Risk ratio: 1.04 3,808 28-day mortality 8,262/39,765 (20.8%) Risk ratio: 0.85 5,143 Supplementary Table 4. Comparison of outcome measures among 39,765 hospitalised patients aged 20-75, who required supplemental oxygen in the first 3 days in hospital. The estimated treatment effect is for a 15% relative reduction in mortality
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