166 Chapter 7 1 2 3 4 4 Hosp 5 Ox 6 CPAP/HFNO 7 IMV 8 IMV S/F<2 9 MOF 10 Dead WHO ordinal severity scale S/F94 day5 Unselected patients (N=12651) 1 2 3 4 Discharge Death S/F94 day0 Unselected patients (N=183380) 1 2 3 4 Discharge Death S/F94 day0 Selected patients (N=49727) 1 2 3 4 Discharge Death S/F94 day5 Unselected patients (N=38877) 1 2 3 4 Discharge Death S/F94 day5 Selected patients (N=11479) a) S/F₉₄ on Day 5 by WHO ordinal scale b) S/F₉₄ on Day 0 d) S/F₉₄ on Day 0 c) S/F₉₄ on Day 5 e) S/F₉₄ on Day 5 Supplementary Figure 5. Relationship between (a) Distribution of S/F94 values day 5 compared with WHO ordinal scale value at the same time point. For some patients who died on day 5, S/F94 values were available. (b) 28day outcome and S/F94 on day 0 and (c) 28-day outcome and S/F94 on day 5 among selected patients meeting inclusion criteria (age 20-75; oxygen therapy in first 3 days) (d) 28-day outcome and S/F94 on day 0 and (e) 28-day outcome and S/F94 on day 5 among unselected patients. Hosp = hospitalised, no oxygen support; Ox = Hospitalised, oxygen by mask or nasal prongs; CPAP/HFNO = Hospitalised, oxygen by continuous positive airway pressure; high-flow nasal oxygen or non-invasive ventilation; IMV = Intubation and mechanical ventilation; IMV S/F ≤ 2 = Mechanical ventilation; S/F ≤ 2 or vasopressors; MOF = Multi-organ failure & mechanical ventilation & S/F94 ≤ 2 & ECMO or renal replacement therapy.
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