405 Health-related quality of life following [18F]FDG-PET/CT 7 Table 7. Mixed linear modelling of changes in RAND-36 scores Baseline (Intercept) Change over time (slope) Assessment, scale B SE p (between group)* B SE p (within group)† p (between group)§ RAND-36 Physical Functioning Malignant 84.6 4.1 0.71 -0.9 1.1 0.42 0.65 Benign 86.5 2.7 ref -1.5 0.7 0.04 ref Active surveillance 80.6 5.1 0.28 0.6 0.9 0.53 0.12 Social Functioning Malignant 75.4 6.0 0.96 -0.7 1.9 0.72 0.82 Benign 75.7 3.7 ref -1.2 1.2 0.31 ref Active surveillance 81.0 5.5 0.46 0.4 1.2 0.76 0.47 Role Functioning - Physical Malignant 75.6 6.0 0.36 -3.0 1.9 0.11 0.48 Benign 69.2 3.8 ref -1.5 1.2 0.19 ref Active surveillance 76.5 6.2 0.33 0.0 1.2 0.98 0.48 Role Functioning - Emotional Malignant 69.0 6.0 0.91 1.8 1.7 0.29 0.55 Benign 68.2 3.7 ref 0.6 1.1 0.61 ref Active surveillance 77.9 5.9 0.19 1.2 1.7 0.45 0.76 Mental Health Malignant 72.5 4.5 0.55 0.7 1.3 0.61 0.24 Benign 69.4 2.7 ref -1 0.7 0.18 ref Active surveillance 72.3 4.2 0.59 0.5 1.1 0.64 0.29 Vitality Malignant 63.5 4.4 0.42 -0.9 1.4 0.49 0.98 Benign 59.8 2.8 ref -1 0.8 0.23 0.37 Active surveillance 60.3 4.1 0.89 0.4 1.1 0.72 0.37 Pain Malignant 80.0 5.4 0.36 0.0 1.7 0.99 0.32 Benign 85.5 3.2 ref -1.9 1.0 0.07 ref Active surveillance 83.6 5.5 0.77 -0.7 1.3 0.57 0.56 General Health Malignant 65.9 4.1 0.65 0.2 1.1 0.86 0.77 Benign 63.6 2.7 ref -0.2 0.7 0.82 ref Active surveillance 57.5 5.1 0.26 1.2 1 0.22 0.30 Health Change Malignant 36.5 6.5 0.30 5.6 2.4 0.02 0.32 Benign 44.6 4.3 ref 2.6 1.7 0.12 ref Active surveillance 45.3 6.3 0.93 3.6 2.0 0.07 0.73 PCS Malignant 51.3 2.0 0.71 -0.6 0.5 0.29 0.84 Benign 52.2 1.1 ref -0.7 0.3 0.02 ref Active surveillance 49.3 2.4 0.23 0.0 0.4 0.96 0.23 MCS Malignant 45.0 2.2 0.45 0.3 0.6 0.59 0.53 Benign 43.1 1.3 ref -0.1 0.4 0.77 ref Active surveillance 47.0 2.0 0.15 0.4 0.5 0.49 0.52
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