396 chapter 7 Table 3. Longitudinal changes and univariate differences between groups in RAND-36 scale scores Patient score, between-group differences Baseline 3 months 6 months 12 months RAND-36 mean SD p* mean SD p* mean SD p* mean SD p* Physical Functioning Malignant 85.0 19.2 0.83 82.0 20.0 0.88 79.5 23.5 0.74 82.9 18.3 0.77 Benign 86 19.6 ref 82.7 20.6 ref 81.2 23 ref 81.6 22.5 ref Active surveillance 81.2 23.8 0.38 82.3 21.9 0.94 80.9 24.4 0.96 83.5 22.8 0.73 Social Functioning Malignant 76.9 26.3 0.74 72.1 29.1 0.44 70.2 29.3 0.80 75.3 28.2 0.74 Benign 78.8 22.8 ref 67.1 32.3 ref 71.9 29.8 ref 73.2 27.7 ref Active surveillance 81.5 24.7 0.64 82.4 26.9 0.02 80.7 25.8 0.16 83.3 21.8 0.07 Role Functioning - Physical Malignant 74.8 27.6 0.73 67.8 31.5 0.20 63.8 27.6 0.97 66.3 28.0 0.98 Benign 72.7 26.6 ref 59.0 30.4 ref 63.6 30.3 ref 66.1 29.2 ref Active surveillance 76.4 29.3 0.59 76.3 27.6 0.01 77.1 27.7 0.04 76.0 26.8 0.13 Role Functioning - Emotional Malignant 72.8 32.0 0.94 70.8 29.2 0.40 71.8 29.2 0.50 78.4 25.8 0.41 Benign 72.4 25.5 ref 65.4 29.5 ref 67.2 33.5 ref 73.7 26.8 ref Active surveillance 78.4 27.5 0.34 81.7 24.3 0.007 80.9 24.3 0.06 82.8 20.2 0.08 Mental Health Malignant 76.1 20.4 0.10 70.1 24.5 0.56 72.8 23.2 0.15 77.4 18.0 0.009 Benign 69.1 17.4 ref 67.0 23.1 ref 65.5 23.1 ref 65.5 23.1 ref Active surveillance 74.1 17.9 0.23 71.4 22.3 0.42 73.8 17 0.06 75.1 16.3 0.04 Vitality Malignant 63.9 21.4 0.40 60.2 20.8 0.29 59.7 21.3 0.52 60.9 20.9 0.30 Benign 60.0 20.9 ref 55.3 22.2 ref 56.6 22.5 ref 56.3 20.3 ref Active surveillance 61.3 20.3 0.80 60.1 18.8 0.31 61.8 13.8 0.18 62.1 16.7 0.17 Pain Malignant 83.2 22.6 0.59 75.7 28.4 0.75 78.6 27.2 0.64 82.2 27.4 0.51 Benign 85.8 18.5 ref 77.7 24.2 ref 81.3 26.8 ref 78.3 26.8 ref Active surveillance 82.8 25.1 0.59 81.9 25.5 0.48 82.0 24.7 0.92 80.3 22.4 0.73 General Health Malignant 67.9 18.6 0.30 65.2 22.3 0.62 63.3 21.5 0.94 69.2 20.0 0.15 Benign 63.6 20.2 ref 62.8 20.6 ref 63.7 24.6 ref 62.8 22.2 ref Active surveillance 58.6 22.8 0.35 60.7 22.4 0.68 59.4 23.8 0.46 63.0 24.3 0.97 Health Change Malignant 44.1 26.7 0.59 46.6 29.4 0.62 49.4 34.7 0.62 61.7 31.3 0.35 Benign 47.0 25.7 ref 49.6 26.1 ref 53.4 39.4 ref 54.3 41.7 ref Active surveillance 45.5 25.1 0.80 55.0 23.5 0.35 61.6 28.2 0.26 55.3 24.5 0.90 Physical Component Score Malignant 51.5 9.4 0.78 49.6 10.0 0.94 48.6 10.5 0.40 50 9.1 0.84 Benign 52.1 8.2 ref 49.7 8.2 ref 50.5 9.5 ref 49.6 10.1 ref Active surveillance 49.2 10.8 0.24 49.6 11.0 0.95 49.0 11.5 0.56 49.5 11.4 0.96 Mental Component Score Malignant 46.3 12.1 0.37 44.5 11.4 0.25 45.2 11.6 0.22 47.2 9.2 0.09 Benign 44.1 9.4 ref 41.7 10.8 ref 42.1 11.6 ref 43.6 10.1 ref Active surveillance 47.7 8.4 0.08 47.3 9.7 0.02 48.0 9.3 0.01 48.6 7.3 0.009
RkJQdWJsaXNoZXIy MTk4NDMw