379 [18F]FDG-PET/CT: cost-utility analysis alongside an RCT 6 Table 6. Estimated 1-year and lifelong societal costs per patient [18F]FDG-PET/CT-driven group (n=91) Diagnostic surgery group (n=41) mean costs per patient (95% CI) mean costs per patient (95% CI) mean difference (95% CI) pa First year societal costs Medical costs Thyroid nodule-related care Regular care €6,100 (€5,400-€6,800) €7,400 (€6,600-€8,100) -€1,300 (-€2,300--€300) 0.01 Care related to [18F]FDG-PET incidental findings €200 (€50-€350) -€50 (-€100-+€0) €200 (-€50-+€400) 0.01 Care related to surgical complications €250 (€50-€400) €200 (€0-€400) €0 (-€250-+€250) 0.94 Subtotal Thyroid nodule-related care €6,500 (€5,700-€7,300) €7,600 (€6,800-€8,300) -€1,000 (-€2,100-€0) 0.06 Other health care consumption €2,200 (€1,500-€3,000) €3,200 (€1,100-€5,200) -€1000 (-€3,000-+€1,100) 0.36 SUBTOTAL Medical costs €8,700 (€7,600-€9,800) €10,700 (€8,500-€13,000) -€2,000 (-€4,400-+€400) 0.10 Patient costs Travel expenses €150 (€150-€200) €200 (€100-€300) -€50 (-€150-+€50) 0.31 Informal care €450 (€100-€850) €900 (€150-€1,700) -€450 (-€1,300-+€350) 0.27 SUBTOTAL Patient costs €650 (€250-€1,000) €1,100 (€350-€1,900) -€500 (-€1,300-+€300) 0.23 Productivity losses Paid productivity losses €5,200 (€3,800-€6,500) €6,800 (€4,300-€9,300) -€1,600 (-€4,400-+€1,200) 0.25 Unpaid productivity loss €1,000 (€600-€1,400) €1,400 (€700-€2,200) -€400 (-€1,200-+€450) 0.35 SUBTOTAL Productivity losses €6,200 (€4,750-€7,650) €8,200 (€5,500-€10,950) -€2,050 (-€5,100-+€1,050) 0.19 TOTAL First year societal costs €15,500 (€13,400-€17,700) €20,100 (€15,800-€24,300) -€4,500 (-€9,200-+€150) 0.06
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