263 Diagnostic utility of molecular and imaging biomarkers 2 Figure 88. SROC curve of [18F]FDG-PET/CT in non-oncocytic nodules Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of [18F]FDG-PET/ CT in non-oncocytic indeterminate thyroid nodules with available histopathology. AUC = AUC = 0.91 (95% CI: 0.88-0.93). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 89. Bayesian probability plot of [18F]FDG-PET/CT in non-oncocytic nodules Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of [18F]FDGPET/CT to predict malignancy in non-oncocytic indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 2.09 (95% CI: 1.35-3.25). Negative LR = 0.13 (95% CI: 0.06-0.30).
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