233 Diagnostic utility of molecular and imaging biomarkers 2 Figure 70. SROC curve of TIRADS Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of TIRADS in indeterminate thyroid nodules with available histopathology. AUC = 0.66 (95% CI: 0.62-0.70). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 71. Bayesian probability plot of TIRADS Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of TIRADS to predict malignancy in indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 1.07 (95% CI: 0.92-1.25). Negative LR = 0.51 (95% CI: 0.24-1.08).
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