225 Diagnostic utility of molecular and imaging biomarkers 2 Figure 68. Bayesian probability plots of individual ultrasound characteristics Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of individual ultrasound characteristics to predict malignancy in indeterminate thyroid nodules (left column), including Bethesda III and IV subgroups (middle and right columns, respectively), using the estimated summary likelihood ratios. Solitary nodule all indeterminate thyroid nodules Bethesda III nodules Bethesda IV nodules Solid appearance Hypoechogenicity n.a.c. LR+ = 1.06 (0.77-1.45) LR- = 0.95 (0.73-1.25) LR+: positive likelihood ratio. LR-: negative likelihood ratio. n.a.: not applicable. n.a.c.: not able to calculate. LR+ = 1.17 (1.09-1.25) LR- = 0.58 (0.47-0.71) LR+ = 0.98 (0.54-1.78) LR- = 1.02 (0.58-1.78) LR+ = 1.13 (1.07-1.19) LR- = 0.48 (0.34-0.69) LR+ = 1.05 (0.91-1.20) LR- = 0.88 (0.62-1.25) LR+ = 1.63 (1.39-1.92) LR- = 0.61 (0.53-0.71) LR+ = 2.46 (1.59-3.79) LR- = 0.53 (0.38-0.73) LR+ = 1.53 (1.16-2.01) LR- = 0.68 (0.54-0.86)
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