212 chapter 2 Figure 64. SROC curve of Galectin-3 and HBME-1 ICC Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of Galectin-3 and HBME-1 ICC in indeterminate thyroid nodules with available histopathology. AUC = 0.89 (95% CI: 0.86-0.91). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 65. Bayesian probability plot of Galectin-3 and HBME-1 ICC Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of Galectin-3 and HBME-1 ICC to predict malignancy in indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 13.47 (95% CI: 3.60-50.42). Negative LR = 0.25 (95% CI: 0.15-0.41).
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