210 chapter 2 Figure 61. SROC curve of Galectin-3 and/or HBME-1 ICC Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of Galectin-3 and/or HBME-1 ICC in indeterminate thyroid nodules with available histopathology. AUC = 0.97 (95% CI: 0.95-0.98). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 62. Bayesian probability plot of Galectin-3 and/or HBME-1 ICC Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of Galectin-3 and/or HBME-1 ICC to predict malignancy in indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 4.51 (95% CI: 2.92-6.97). Negative LR = 0.04 (95% CI: 0.01-0.12).
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