207 Diagnostic utility of molecular and imaging biomarkers 2 sensitivity (95% CI), % specificity (95% CI), % LR+ (95% CI) LR- (95% CI) 88 (53-98) 100 (74-100) 20.00 (1.31-306.39) 0.17 (0.04-0.75) 76 (65-84) 90 (79-96) 7.60 (3.28-17.63) 0.27 (0.18-0.40) 83 (44-97) 80 (61-91) 4.17 (1.76-9.86) 0.21 (0.03-1.26) 78 (70-87) 91 (81-101) 6.07 (3.18-11.57) 0.26 (0.17-0.38) Figure 59. Estimated pooled test performance of CK-19 ICC Forest plots showing the estimated pooled sensitivity (a) and specificity (b) with their corresponding 95% confidence intervals of CK-19 ICC in indeterminate thyroid nodules with available histopathological follow-up. CI, confidence interval; I^2, heterogeneity statistic I2. a. b.
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