201 Diagnostic utility of molecular and imaging biomarkers 2 Figure 54. SROC curve of Galectin-3 ICC Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of Galectin-3 ICC in indeterminate thyroid nodules with available histopathology. AUC = 0.90 (95% CI: 0.87-0.92). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 55. Bayesian probability plot of Galectin-3 ICC Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of Galectin-3 ICC to predict malignancy in indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 7.97 (95% CI: 4.25-14.95). Negative LR = 0.29 (95% CI: 0.20-0.42).
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