185 Diagnostic utility of molecular and imaging biomarkers 2 Figure 45. Estimated pooled test performance of the Afirma® GEC – best-case scenario Forest plots showing the estimated pooled sensitivity, specificity, positive and negative likelihood ratios with their corresponding 95% confidence intervals of the Afirma® GEC in a hypothetical best-case scenario in which we presumed that the Afirma® GEC was always right in indeterminate thyroid nodules without available histopathological correlation. CI, confidence interval; df, degrees of freedom; DLR positive, positive diagnostic likelihood ratio; DLR negative, negative diagnostic likelihood ratio; I2, heterogeneity statistic I2; Q, Cochran’s Q.
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