142 chapter 2 Figure 21. SROC curve of PAX8/ PPARγ rearrangement analysis Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of PAX8/ PPARγ rearrangement analysis in indeterminate thyroid nodules with available histopathology. AUC = 0.12 (95% CI: 0.10-0.15). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 22. Bayesian probability plot of PAX8/PPARγ rearrangement analysis Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of PAX8/ PPARγ rearrangement analysis to predict malignancy in indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 19.44 (95% CI: 3.17-119.27). Negative LR = 0.94 (95% CI: 0.92-0.97).
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