130 chapter 2 Figure 17. Estimated pooled test performance of RAS mutation analysis – Bethesda IV Forest plots showing the estimated pooled sensitivity, specificity, positive and negative likelihood ratios with their corresponding 95% confidence intervals of RAS mutation analysis in Bethesda IV thyroid nodules with available histopathological follow-up. CI, confidence interval; df, degrees of freedom; DLR positive, positive diagnostic likelihood ratio; DLR negative, negative diagnostic likelihood ratio; I2, heterogeneity statistic I2; Q, Cochran’s Q.
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