125 Diagnostic utility of molecular and imaging biomarkers 2 Figure 13. SROC curve of RAS mutation analysis Summary receiver operating characteristic plot showing sensitivity versus 1-specificity of RAS mutation analysis in indeterminate thyroid nodules with available histopathology. AUC = 0.83 (95% CI: 0.79-0.86). AUC, area under the curve; HSROC, hierarchical summary receiver operating characteristic. Figure 14. Bayesian probability plot of RAS mutation analysis Bayesian conditional probability plot showing the post-test probabilities versus prior probabilities of RAS mutation analysis to predict malignancy in indeterminate thyroid nodules, using the estimated summary likelihood ratios. Positive LR = 4.87 (95% CI: 2.67-8.90). Negative LR = 0.77 (95% CI: 0.66-0.89).
RkJQdWJsaXNoZXIy MTk4NDMw