TABLE OF CONTENTS Abbreviations 7 Chapter 1 Introduction 9 Chapter 2 Objectives 19 Chapter 3 Non-surgical treatment of prolapse and urinary incontinence 23 3.1 Vaginal laser therapy for pelvic organ prolapse: the VELPOP-study 25 3.2 Vaginal laser therapy for stress urinary incontinence: the VELSUI-study 37 Chapter 4 Surgical treatment of prolapse and urinary incontinence 49 4.1 Cervicosacropexy or vaginosacropexy for urinary incontinence and apical prolapse: 51 A systematic review 4.2 Evaluation and optimization of sacrocolpopexy as surgical treatment for apical prolapse 67 4.2.1 Long-term Data on Graft-Related Complications After Sacrocolpopexy With Lightweight 69 Compared With Heavier-Weight Mesh 4.2.2 Safety and medium-term outcome of redo laparoscopic sacrocolpopexy: a matched 83 case–control study 4.2.3 Cost of using glue rather than sutures for mesh fixation during sacrocolpopexy 97 4.2.4 An automated workflow analysis to evaluate novel modifications and learning curves 107 in sacrocolpopexy Chapter 5 Discussion 119 Chapter 6 Summary 127 Chapter 7 References 135 Chapter 8 Scientific Acknowledgement, Personal Contribution and Conflict of Interest 147 statements Chapter 9 Curriculum vitae 153 Acknowledgement - dankwoord 159
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