Glue CMA 101 single vial of 1.5 mL of glue is enough for this procedure. Glue was applied using a dedicated applicator (Figure 1). As in other studies, a number of sutures were placed to keep the mesh from slipping and for the glue to stick well (maximum two on the anterior and two on the posterior vault, and in case of concomitant rectopexy, two on the rectum).186-192 Additional patient data were collected from the electronic medical record (Nexuzhealth, Hasselt, Belgium). Costs were measured using the data of the “Activity Centre – Care program model”.195 This model calculates the direct costs of patients' care pathways within the hospital, taking into account the bill of activity (BOA) of a patient during the stay. The model uses a cost per unit per activity center. Costs were categorized as either consumables or operating room costs. he latter include costs of medical and non-medical staff and fixed costs of maintenance contracts. During the study period, the costs of the sutures, glue vials and exploitation of the operation room did not change. Therefore, only the direct costs are relevant to this type of study, calculating only differences in costs. The indirect costs were assumed not being impacted by the use of different closing techniques. Statistical analysis was performed using GraphPad Prism version 9.0 for Windows (GraphPad Software, San Diego, California, USA). The chi-square test or t-test were used as appropriate, with a significance level set at p<0.05. This audit was approved by the local Ethics Committee (B322202042753) and prospectively registered at clinicaltrials.gov (NCT04378400). Informed consent was obtained from all participants. Figure 1: The posterior mesh glue fixation technique. Glue was applied using a dedicated applicator.
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