72 Chapter 5 diagnosed with VWD (n=1), a Factor VII-deficiency (FVII, n=1) or carriership of hemophilia (n=1), with total self-BAT scores being 11 (30 yrs); 3 (18 yrs); and 4 (18 yrs), respectively. Total and domain-specific self-BAT scores The total self-BAT scores ranged from 2 to 17 (Table 2). The overall prevalence of an abnormal total self-BAT score was 68% (157/231). All self-BAT domains had a median score of 0 across all age groups, the most reported bleeding events were the domains ‘oral cavity’ and ‘menorrhagia’ (Table 2). Self-BAT scores per HMB treatment outcome Medical HMB treatment consisted of tranexamic acid (TXA), iron, hormonal (levonorgestrel devices, oral hormonal treatment) or combined (TXA and hormonal) therapy. (Table 3 on women aged 18-30 yrs and Table 4 on women aged 31-52 yrs). Iron supplementation for HMB was less often prescribed, namely in 16% of women (36/231). However, TXA and iron were more often prescribed in the self-BAT score ≥5 (18-30 yrs) or ≥6 groups (31-52 yrs), albeit not being statistically significant. Many women received hormonal treatment (68/231; 29%). The prevalence of an abnormal self-BAT score in the ‘Hormonal + TXA group’ versus ‘no Hormonal + TXA group’ was statistically significant different between groups <5 or ≥5 (women 18-30 years) (OR 0.11; 95% CI,0.0; 0.9; p=0.04) (Table 3). Table 1: Demographic variables per age group. Variable All respondents (n=231) 18-30yrs (n=27) 31-41yrs (n=58) 42-52yrs (n=146) Age, mean (± SD) 42 (± 9) 24 (± 4) 36 (± 3) 47 (± 3) Positive family history bleeding disorder, n (%) 2 (0) 0 (0) 2 (3) 0 (0) Anticoagulant use, n (%) 0 (0) 0 (0) 0 (0) 0 (0) General health All respondents (n=188) 18-30yrs (n=21) 31-41yrs (n=57) 42-51yrs (n=110) Smoking, n (%) 21 (11) 0 (0) 11 (19) 10 (9) Sport >2h/wk, n (%) 107 (57) 13 (62) 33 (58) 57 (52) Alcohol <7 unit/wk, n (%) 70 (37) 5 (24) 24 (42) 41 (37) Blood group 0, n (%) 56 (30) 6 (29) 16 (28) 34 (31) BMI kg/m2, median (IQR) 26 (24-29) 26 (23-30) 26 (24- 27) 28 (25-29) Legend: SD, standard deviation; IQR, interquartile range, BMI; Body mass index.
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