68 Chapter 3 Adhesive small bowel obstruction (SBO) In total, 99 studies reported on small bowel obstruction entailing 8470 patients and 572 events of SBO all anomalies combined [35, 49, 57, 60, 62, 65, 71, 83, 84, 87, 88, 95, 96, 108, 112, 117, 120, 121, 123, 140, 141, 143, 145, 153, 161, 166, 184, 205, 207-212, 215, 217, 218, 220, 222-227, 230, 232-235, 237-239, 242, 244-246, 249, 250, 253-255, 258, 259, 261-263, 265-270, 272, 274-278, 280, 281, 283-285, 287-299, 301, 302, 304-307]. Length of follow up was at least half a year in 56 (57%) of the studies. The pooled proportion of total SBO was 0.06 (95%-CI: 0.05-0.07; I2 = 74%, p ≤ 0.01). Separate proportions were calculated for the following conditions: Hirschsprung’s disease 0.05 (95%-CI: 0.03-0.07; n=174/3044; I2 = 77%; p ≤ 0.01); gastroschisis 0.09 (95%- CI: 0.06-0.14; n=130/1147; I2 = 75%; p ≤ 0.01); congenital diaphragmatic hernia 0.08 (95%-CI: 0.06-0.11; n=60/736; I2 = 35%; p = 0.09); duodenal obstruction 0.04 (95%-CI: 0.02-0.08; n=28/728; I2 = 61%; p = 0.01); small intestinal atresia 0.09 (95%-CI: 0.05-0.14; n=60/690; I2 = 74%; p ≤ 0.01); biliary atresia 0.03 (95%-CI: 0.02-0.05; n=19/543; I2 = 0%; p = 0.48); malrotation 0.11 (95%-CI: 0.06-0.19; n=46/492; I2 = 73%; p ≤ 0.01); anorectal malformations 0.03 (95%-CI: 0.02-0.06; n=17/476; I2 = 37%; p = 0.54); omphalocele 0.04 (95%-CI: 0.02-0.24; n=21/357; I2 = 51%; p = 0.31); choledochal cyst 0.03 (95%-CI: 0.010.08; n=5/143; I2 = 0%; p = 0.48). Meconium ileus (N=54), Meckel’s diverticula (N=46) and colonic atresia (N=14) are included in the overall proportion but did not meet the criteria for separate statistical analysis (Figure 3). Figure 3 - Pooled proportion of small bowel obstruction
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