Laurens Schattenkerk

213 Should primary anastomosis be feared less? A retrospective analysis of anastomotic complications in young children Chapter 9 Table 3 - Characteristics of anastomotic complications Anastomotic stenosis (Total = 34) Anastomotic leakage (Total = 22) Count (% of total) (Missing = N) Count (% of total) (Missing = N) Male sex 14 (41%) 18 (82%) ASA ≥III score prior to operation 7 (27%) (Missing = 8) 9 (53%) (Missing = 5) Location of anastomosis Small intestine 11 (32%) 13 (65%) (Missing = 2) Ileocolic 5 (15%) 5 (23%) Colon 18 (53%) 3 (14%) Type of anastomosis End-to-End 29 (85%) 12 (57%) (Missing = 1) End-to-Side 0 0 Side-to-Side 3 (8%) 5 (23%) Closed longitudinal incision intestine 2 (5%) 5 (23%) Stapled 0 0 Technique of handsewn sutures Continuous 11 (37%) (Missing = 4) 10 (67%) (Missing = 7) Interrupted 19 (63%) 5 (33%) Suture resorption time Normal 12 (41%) (Missing = 4) 6 (38%) (Missing = 6) Slow 17 (59%) 10 (62%) Median days until the complication (IQR) 44 (25-209) 6 (4-7) Re-operation needed 23 (68%) 21 (96%) Death related to complication 3 (9%) 2 (9%) Recurrence in surviving patients 1 (5%) 0 Table 4 – Cox regression into technical factors associated with anastomotic stenosis Variable Hazard ratio (95%-CI) P value Location of anastomosis Small intestine Comparator Comparator Ileocolic 1.6 (0.6 – 4.6) P = 0.54 Colon 3.0 (95%-CI: 1.4-6.7) P ≤ 0.01 Type of anastomosis Side-to-Side Comparator Comparator End-to-End 2.0 (0.9 – 4.5) P = 0.07 End-to-Side 1.2 (0.1 – 11.4) P = 0.89 Handsewn anastomosis Suture resorption time 1.4 (0.50 – 4.4) P = 0.53 Mode of suturing 0.5 (0.3 – 1.3) P = 0.23

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