175 Incisional hernia after abdominal surgery in infants: A retrospective analysis of incidence and risk factors Chapter 7 wound infection (OR: 5.3, 95%-CI: 2.9-9.5), premature birth (OR: 4.2, 95%-CI: 2.6-6.7) and history of a stoma (OR 1.7, 95%-CI: 1.1-2.8) were significantly associated with IH. The model yields an adjusted R2 of 17% and the Hosmer-and-Lemeshow test was nonsignificant (p = 0.64). Subgroup analysis The first subgroup analysis looked into IH following different surgical approaches. Out of all IHs following laparoscopy (16/107), 38% (6/16) of these were early IHs. 50% (8/16) of the IHs following laparoscopy occurred following laparoscopic PS treatment, 50% (4/8) of these were early IHs. Between IHs following these surgical approaches there was no significant difference between preterm birth (p = 0.772) and wound infection (p = 0.345). The second subgroup analysis evaluated if the distribution of technical factors significantly differed between infants that did or did not develop an IH following laparotomy. There was no difference in the occurrence of IH between midline and transversal incision (p = 0.802), between slow and normal suture resorption speed (p = 0.303), between monofilament and braided sutures (p=0.382) and between continuous or intermittent closure (p = 0.974). Distribution risk factors over time We split the cohort into five time intervals, each four consecutive years, to evaluate if the distribution of incidences and risk factors significantly changed over time. This was not the case for the incidence of IH (p = 0.15), the incidence of necrotizing enterocolitis (p = 0.08), post-operative wound infection (p = 0.16) and preterm birth (p = 0.11). Having a history of stoma (p = 0.01) did show a significant decrease over time (Figure 1). The number of patients with gastroschisis and omphalocele per time interval were too small to be included in this analysis.
RkJQdWJsaXNoZXIy MTk4NDMw