Laurens Schattenkerk

164 Chapter 6 Conclusion A CLABSI occurs in approximately a third of the patients treated for intestinal atresia or gastroschisis whilst a catheter related thrombosis occurs in one in fourteen patients. When in doubt which catheter to use for the administration of parenteral nutrition in these patients, a tunnelled catheter is preferred over a non-tunnelled since it is comparatively less at risk of catheter related infections and thrombosis. Moreover, the risk of CLABSI in this group of patients is increased following enterostomy formation. Besides adherence to uniform guidelines, it might be that a change in preventive measures for CLABSI, such as taurolidine as a line-lock infusion, and for thrombosis, such as starting low molecular weight heparin in when catheter dwell time is expected for shorter than six weeks, would decrease the occurrence of these complications in this cohort of patients. For this, well designed trials are necessary for these specific patients.

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