154 | Chapter 6 Table 1. Continued Experts Age (mean, range) 46 years (30 – 59) Gender Female Male 10 (50%) 10 (50%) Specialty RO HNS SLP PT CE 7 (35%) 7 (35%) 2 (10%) 2 (10%) 2 (10%) Work experience (mean, range) 14 years, (5 – 26) PDA experience None One Multiple 4 (20%) 14 (70%) 2 (10%) Included per phase** Phase 1 Phase 2 Phase 3 N (%), N cumulative 10 (50%), 10 7 (35%), 16 3 (15%), 18 *Of which 1 patient obtained a doctorate. ** The numbers do not add up to 20 because one RO only participated in phase 1 and one SLP only participated in phase 2. ND = neck dissection, RT = radiation therapy, TO(R)S = transoral (robotic) surgery, PORT = post-operative radiation therapy, RO = radiation-oncologist, HNS = Head-and-Neck surgeon, SLP = speech-and-language pathologist, PT = physiotherapist, CE = communication expert Phase 1: Gathering information Literature and Counseling materials We focused on randomized studies comparing radiation and surgery in early-stage OPSCC. The ‘ORATOR trial’15 and the ‘BEST OF’ trial16 are both studies investigating the best treatment for this patient group. The ‘BEST OF’ trial is still ongoing. Results of the ‘ORATOR’ trial are analyzed and compared to our ‘inclusion criteria’ and used as background information. Preferably we wanted to use Dutch survival rates, but there were no reliable numbers available. After discussion with the steering group, it was decided that the survival numbers from the ‘ICON-S’ study are most accurate and therefore used in the PDA17.
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