PDA Impact in Advanced Larynx Cancer | 133 5 Table 1. Characteristics of both study arms Patients Usual care (n=45) N (%) Intervention (n=46) N (%) p-value** Age (years): Mean (SD), range 64.3 (9.8), 48-91 68.2 (10.8), 41-86 0.113 Sex: Male Female 34 (75.6) 11 (24.4) 35 (76.1) 11 (23.9) 0.953 TN-classification*: T3N0 T3N+ T4N0 T4N+ 21 (46.7) 5 (11.1) 13 (28.9) 6 (13.3) 22 (47.8) 13 (28.3) 6 (13) 5 (10.9) 0.101 Subsite: Supraglottic Glottic Transglottic Subglottic 28 (62.2) 11 (24.4) 3 (6.7) 3 (6.7) 29 (63) 15 (32.6) 1 (2.2) 1 (2.2) 0.454 Educational level: Lower educational level Intermediate educational level Higher educational level 24 (53.3) 18 (40) 3 (6.6) 39 (84.8) 7 (15.2) 0 (0) 0.468 Occupational status: Yes No Sickness benefits law / Sickness insurance law Retired 8 (17.8) 16 (35.6) 2 (4.4) 19 (42.2) 6 (13) 9 (19.6) 2 (4.3) 29 (63) 0.229 Access to internet Yes No 39 (86.7) 6 (13.3) 41 (89.1) 5 (10.9) 0.689 Treatment received: RT CRT (cis/cet) TL + RT TL Best supportive care 16 (35.6) 12 (26.7) 14 (31.1) 3 (6.7) 0 (0) 24 (52.2) 10 (21.7) 8 (17.4) 2 (4.3) 2 (4.3) 0.346 Abbreviations: SD= Standard Deviation; N = sample size; TN = Tumor, Node; RT = radiotherapy; CRT = chemoradiation, cis = cisplatin; cet = cetuximab; TL = total laryngectomy. *TN-classification; TN-classification was documented instead of TNM-classification since the presence of distant metastasis (M) was an exclusion criterium. **All testing was performed with chi-square, except an unpaired t-test for age
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